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3 tools

Variant calling Tools

Discover our collection of 3 research tools and applications for variant calling.

Related Categories

Genetic variation2
DNA polymorphism2
GWAS study1
Genotyping experiment1
Data handling1
Whole genome sequencing1
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Tools in Variant calling

Found 3 of 3 tools

BCFtools

https://spdx.org/licenses/MIT
Code Repository

BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed.

DeepVariant

https://spdx.org/licenses/BSD-3-Clause
Code Repository

DeepVariant is a deep learning-based variant caller that takes aligned reads (in BAM or CRAM format), produces pileup image tensors from them, classifies each tensor using a convolutional neural network, and finally reports the results in a standard VCF or gVCF file.

Strelka2

https://spdx.org/licenses/GPL-3.0-or-later.html
Code Repository

Strelka is an analysis package designed to detect somatic SNVs and small indels from the aligned sequencing reads of matched tumor-normal samples.